Tachipirinaflu Adulti 500+200 mg 12 Compresse

Therapeutic indications

Symptomatic therapy of influenza and fever of all kinds (fever resulting from colds, exanthematous or infectious diseases). As an analgesic for rheumatic joint and muscle pain, neuralgia, headache and menstrual pain.

Dosage

TACHIPIRINAFLU is not indicated for children and adolescents under 18 years of age. Adults Posology 1 effervescent tablet at a time, to be repeated if necessary after 4 hours, without exceeding 6 doses per day. In case of severe pain or high fever, take 2 effervescent tablets to be repeated if necessary after not less than 4 hours. Do not administer for more than 3 consecutive days without consulting your doctor. Method of administration The effervescent tablet should be dissolved in a glass of water.

Overdose

There is a risk of intoxication, especially in patients with liver disease, in cases of chronic alcoholism, in patients with chronic malnutrition, and in patients receiving enzyme inducers. In these cases, overdose can be fatal. Symptoms In case of accidental intake of very high doses of paracetamol, acute intoxication is manifested by anorexia, nausea and vomiting followed by a profound deterioration of the general conditions; these symptoms usually appear within the first 24 hours. In case of overdose, paracetamol can cause hepatic cytolysis which can evolve towards massive and irreversible necrosis, with consequent hepatocellular insufficiency, metabolic acidosis and encephalopathy, which can lead to coma and death. Simultaneously, an increase in hepatic transaminase levels, lactic-dehydrogenase, and bilirubin levels, and a decrease in prothrombin levels are observed, which may occur 12–48 hours after ingestion. Treatment The measures to be adopted consist of early gastric emptying and hospitalization for appropriate treatment, by administering, as early as possible, N-acetylcysteine as an antidote: the dosage is 150 mg / kg iv in a glucose solution in 15 minutes. , then 50 mg / kg in the next 4 hours and 100 mg / kg in the next 16 hours, for a total of 300 mg / kg in 20 hours.

Contraindications

- Hypersensitivity to paracetamol or vitamin C, or to any of the excipients listed in section 6.1. - Children and adolescents (less than 18 years of age).

Side effects

The following are the side effects of acetaminophen organized according to the MedDRA systemic and organic classification. Insufficient data are available to establish the frequency of the individual effects listed.

Pregnancy and breastfeeding

Although clinical studies in pregnant or lactating patients have not shown particular contraindications to the use of paracetamol or caused unwanted effects affecting the mother or the child, it is recommended to administer the medicine only in cases of real need and under the direct supervision of the doctor. .

Special warnings

In rare cases of allergic reactions, administration should be discontinued and appropriate treatment instituted. Use with caution in case of chronic alcoholism, excessive alcohol intake (3 or more alcoholic drinks per day), anorexia, bulimia or cachexia, chronic malnutrition (low reserves of hepatic glutathione), dehydration, hypovolemia. Paracetamol should be administered with caution to patients with mild to moderate hepatocellular insufficiency (including Gilbert's syndrome), severe hepatic insufficiency (Child-Pugh> 9), acute hepatitis, concomitantly treated with drugs that impair liver function, deficiency of glucose-6-phosphate dehydrogenase, haemolytic anemia. High or prolonged doses of the drug can cause blood and kidney alterations, even serious ones. Administration in subjects with renal insufficiency should only be carried out if actually necessary and under direct medical supervision. In case of prolonged use it is advisable to monitor liver and kidney function and blood count. During treatment with paracetamol, before taking any other drug, check that it does not contain the same active ingredient, as serious adverse reactions can occur if paracetamol is taken in high doses. Instruct the patient to consult the physician before combining any other drugs (see also section 4.5). Important information about some of the ingredients TACHIPIRINAFLU effervescent tablets contain: - 12.2 mmol (280.5 mg) of sodium per tablet. To be taken into consideration in people with reduced kidney function or who follow a low sodium diet. - sorbitol: patients with rare hereditary problems of fructose intolerance should not take this medicine. - sunset yellow (E110): can cause allergic reactions.

Expiry and Retention

This medicine does not require any special storage conditions.

Active principles

Each effervescent tablet contains: Active ingredients: paracetamol 500 mg and vitamin C 200 mg Excipients with known effects: sorbitol, sunset yellow (E110). For the full list of excipients see section 6.1.

Excipients

Citric acid anhydrous Sodium bicarbonate Sodium carbonate anhydrous Acesulfame K Sorbitol Orange flavor Simethicone emulsion Sodium docusate Sunset yellow (E110)