Screen Drug Test Saliva 6 Multi-Drug Test Detection 6 Substances

Rapid screening test for the simultaneous, qualitative determination of amphetamine, methamphetamine, cocaine, opiates, marijuana, ecstasy and their metabolites in human saliva.

Precautions
• Product not intended for medical or diagnostic use.
• Do not use beyond the expiration date.
• Keep the test strip panel in the closed pouch until ready for use.
• Store in sealed pouch until use.
• Saliva is not classified as a biohazard substance if it does not result from a dental procedure.
• The used wallet and card must be disposed of in accordance with the regulations in force.


Intended Use and Summary
Slide chromatographic immunoassay for the qualitative detection of multiple drugs and metabolites in saliva at the following cut-off concentrations:

Test	Calibrator	Threshold-limit (ng / ml)
Amphetamine (AMP)	d-Amphetamine	40
Methamphetamine (MET)	d-Methamphetamine	40
Marijuana (THC)	11-nor-Δ9-THC-9 COOH	10
Cocaine (COC)	Benzoylecgonine	30
Opiates (OPI / MOP)	Morphine	40
Ecstasy (MDMA)	dl-methylenedioxymethamphetamine	50

This test provides preliminary analytical data only.
More specific chemical methods should be used as confirmation of the analytical result.
Gas chromatography and mass spectrometry (GC / MS) are considered preferential confirmatory methods.
Any drug of abuse finding should be related to clinical considerations and professional judgment, particularly when the preliminary result is positive.

Rapid urine screening test that does not require the use of special tools.
The test uses antibodies to selectively detect high levels of specific substances in human saliva.
The residence times are approximate for each substance as they vary according to the frequency of use, body mass, age, state of health, tolerance to drugs.
The product detects the presence of narcotic substances in saliva only after their metabolization.

COCAINE (COC)
Cocaine is a powerful central nervous system stimulant as well as a local anesthetic derived from the coca plant.
The substance is often self-administered by inhalation or intravenous injection or by smoking the base substance.

AMPHETAMINE (AMP
Amphetamine is a substance also used for therapeutic purposes.
The substance is often self-administered by inhalation or ingestion.
High doses produce enhanced central nervous system stimulation and induce euphoria, alertness, decreased appetite, a sense of increased energy and strength.
More acute reactions produce anxiety, paranoia, hallucinations and psychotic behavior.

METAMPHETAMINE (MET / MDMA)
Methamphetamine is a potent stimulant chemically linked to amphetamine, but with an increased ability to stimulate the central nervous system.
The substance is often self-administered by inhalation, smoking or ingestion.

MARIJUANA (THC)
Tetrahydrocannabinol is the active ingredient in cannabis.
When smoked or taken orally, THC produces euphoria.
Regular users have short-term memory impairment and learning delay, they may also have transient episodes of confusion and anxiety.
Relatively heavy long-term consumption may be associated with behavioral disturbances.

OPIASES (OPI)
The class of opiates refers to any substance derived from the opium poppy, including natural compounds such as morphine, codeine and semi-synthetic substances such as heroin.
Opiates act on pain control by depressing the central nervous system.
Withdrawal symptoms can include sweating, tremors, nausea, and irritability.
Opiates can be taken orally or by intravenous, intramuscular and subcutaneous injection.
Consumers can also take the substance intravenously or by inhalation.

ECSTASY (MDMA)
Synthetic drug, first synthesized in 1914 by a German pharmaceutical company for the treatment of obesity.
Those who use it regularly report side effects such as increased muscle tension and sweating.
MDMA is not a true stimulant, although it has in common with amphetamines an ability to increase blood pressure and heart rate.
MDMA produces some perceptual variations such as increased sensitivity to light, difficulty concentrating and blurred vision in some users.
Its mechanism of action is thought to occur through the release of the neurotransmitter serotonin.
MDMA can also release dopamine, although it is commonly believed that this is a side effect of the substance (Nichols and Oberlender, 1990).
The most obvious effect of MDMA, which potentially occurs in anyone who has taken a reasonable dose of the substance, is the twitching of the jaws.
The test for MDMA contained in the product gives a positive result when the concentration of MDMA in saliva exceeds 50 ng / ml.

PRINCIPLE
It is an immunoassay based on the principle of competitive binding.
Drugs that may be present in the oral fluid sample compete against their respective conjugates for binding sites on the specific antibody.
During the test a part of the saliva sample migrates upwards by capillary action.
A drug, if present in the oral fluid sample below the cut-off concentration, will not saturate the binding sites of this specific antibody.
The antibody will then react with the drug-protein conjugate and a colored line will appear visible in the test area for the specific drug tested. The presence of the drug above the cut-off concentration will saturate all binding sites of the antibody.
Therefore the colored line will not form in the test area.
A positive oral fluid sample will not generate a colored line in the specific test area of the strip due to drug competition, while a negative drug oral fluid sample will generate a line in the test area due to the absence of competition.
For procedural control purposes, a colored line will always appear in the control zone, indicating that the correct volume of sample has been spilled and the membrane has been soaked.

REAGENTS
The test contains membrane strips coated with drug-protein conjugates (purified bovine albumin) on the test line, a polyclonal antibody from goat to gold-protein conjugate on the control line, and a soaked pad that contains gold-colloidal particles coated with antibody mouse monoclonal specific for Amphetamine, Methamphetamine, Cocaine, Opioids, Δ9-thc-cooh, Methadone, Ecstasy and synthetic Marijuana.

STORAGE AND STABILITY
Store in the sealed original package at 2-30 ° C.
The test is stable until the expiration date printed on the package.
The test should remain in the sealed pouch until use.
Do not freeze.
Do not use beyond the expiration date.

COLLECTION AND PREPARATION OF SAMPLES
The oral fluid sample should be collected using the collector provided with the kit.
Follow the detailed instructions below.
Do not use other collection devices for analysis.
Oral fluid can be collected at any time of the day.

INSTRUCTIONS FOR USE
Bring the test, specimen, and / or controls to room temperature (15-30 ° C) prior to testing.
Advise the donor not to put anything in the mouth, including food, drink, gum, or tobacco, for at least 10 minutes prior to collection.
1. Bring the package to room temperature before opening. Remove the test from the sealed pouch and use it within one hour.
2. Remove the test cap and insert the absorbent swab into the mouth, under the tongue, to collect saliva until the control line appears. Extract the test.
3. Place the test on a clean, flat surface. See illustration below. 4. Read the results after 10 minutes. Do not read the results after 1 hour.

INTERPRETATION OF RESULTS
Negative *: All test bands appear. One colored line must be in the control zone (C), while the other must be adjacent to the test zone (Substance / T). The negative result indicates that the concentration of the substance is below the detectable level or absent.
* the hue in the test zone (Substance / T) varies, but must be considered negative even if a faintly colored line appears
Positive: only one colored line appears in the control areas (C). No test band (Substance / T) appears in the test zone. The positive result indicates that the concentration of the substance is above the detectable level.
Invalid: No control line appears. The most likely reasons for the control line not to appear are insufficient sample volume or incorrect procedural techniques. Check the procedure and repeat the test using a new card.
If the test is positive, avoid aggressive behavior and calmly seek a dialogue with the person concerned. Get advice from your doctor, a psychologist or contact the competent service for your area.

QUALITY CHECK
A procedural control is included in the test.
The line appearing in the control region (C) is considered an internal procedural control.
Confirms that sufficient sample volume, adequate membrane imbibition and correct procedural technique were used.

LIMITATIONS
1. The test provides only a qualitative preliminary analytical result. A secondary analytical method should be used to confirm the result. The recommended confirmatory method is gas chromatography / mass spectrometry (GC / MS).
2. A positive test result does not indicate the concentration of the substance in the specimen or the route of administration.
3. A negative result may not necessarily indicate a drug-free sample. Negative results may be obtained when the drug is present below the cut-off point for the test.
4. It is possible that technical or procedural errors, as well as interfering substances in the saliva sample, can cause erroneous results.
5. This test does not distinguish between drugs of abuse and some medications.

FORMAT
• 1 swab.
• 1 Drug Test Saliva 6.
• package leaflet.