Pirestop Powder For Oral Solution Paracetamol Lemon and Honey 10 Sachets

Sachets based on paracetamol, ascorbic acid and phenylephrine hydrochloride.

Therapeutic indications

Pirestop is used in the symptomatic treatment of flu, colds and related feverish and painful states, with a decongestant action on the upper upper airways.

Dosage and Posology

Pirestop is administered as follows:

• Adults and children over 12 years: 1 sachet every 4-6 hours and up to a maximum of 3 sachets in 24 hours.

Dissolve 1 sachet in half a glass of very hot water and, if desired, dilute with cold water to cool and sweeten as desired.

Overdose

At the recommended doses, or even if the entire pack is taken, no symptoms of paracetamol overdose should appear. However, in the case of ingestion of very high doses of paracetamol (greater than 15 g), the most commonly encountered complication is liver damage, which usually occurs 2-4 days after intake. The early symptoms are nausea, vomiting and abdominal pain: the appropriate therapy recommended is gastric lavage using specific antidotes such as acetylcysteine or methionine. More than 10 hours after ingestion, a haemoperfusion may be necessary. Other symptoms of overdose are caused by phenylephrine and are manifested by irritability, headache and increased blood pressure.

Contraindications

• Hypersensitivity to the components of the product or to other related substances from a chemical point of view.
• Children under the age of 12.
• Patients taking beta-blockers, monoamine oxidase inhibitors and tricyclic antidepressants.
• Patients suffering from renal insufficiency, diabetes, hyperthyroidism, hypertension and cardiovascular diseases.

Side effects

Skin reactions of various types and severities have been reported with the use of paracetamol, including cases of erythema multiforme, Stevens Johnson syndrome and epidermal necrolysis. Hypersensitivity reactions such as angioedema, laryngeal edema, anaphylactic shock have been reported. In addition, the following undesirable effects have been reported: thrombocytopenia, leukopenia, anemia, agranulocytosis, liver function abnormalities and hepatitis, kidney disorders (acute renal failure, interstitial nephritis, haematuria, anuria), gastrointestinal reactions and dizziness. With sympathomimetics (phenylephrine) skin irritation, tachycardia, hypertension and much more rarely nausea, vomiting or anorexia may occur occasionally.

Pregnancy and breastfeeding

Use during pregnancy is not contraindicated but requires caution; the administration of the preparation during pregnancy and lactation must take place under the direct supervision of the doctor and in case of real need.

Special warnings

During treatment with paracetamol, before taking any other drug, check that it does not contain the same active ingredient, as serious adverse reactions can occur if paracetamol is taken in high doses. Paracetamol products should be administered with caution to patients with mild to moderate hepatocellular insufficiency (including Gilbert's syndrome), severe hepatic insufficiency, acute hepatitis, concomitant treatment with drugs that impair liver function, glucose deficiency. 6-phosphate dehydrogenase, haemolytic anemia. Instruct the patient to contact the physician before associating any other medication.

It is not recommended to use the product if the patient is being treated with anti-inflammatories. Do not administer for more than 3 consecutive days without consulting your doctor. The drug contains sucrose: patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.

Expiration and retention

Check the expiration date indicated on the package. The expiry date indicated on the package refers to the product in intact packaging, correctly stored. Store below 25 ° C.

Warning : do not use the medicine after the expiry date indicated on the package.

Composition

A 4 gram sachet of Pirestop contains:

Active principle

Paracetamol 600 mg, ascorbic acid 40 mg and phenylephrine hydrochloride 10 mg

Excipients

Sucrose, anhydrous citric acid, sodium citrate, corn starch, anhydrous colloidal silica, sodium cyclamate, sodium saccharin, lemon flavor, honey flavor, caramel flavor.