INDICATIONS Treatment of gastrointestinal infestations of equines caused by large strongyles (Strongylus vulgaris, S. edentatus, S. equinus), small strongyles (Triodonthophorus spp., Cyathostominae) and tapeworms (Tapeworms: Anoplocephala perfoliata, Anoplocephala magna).
CONTRAINDICATIONS / SECONDARY EFFECT Do not use in animals with hypersensitivity to the active substance or to any of the excipients. Its use is not recommended in severely debilitated animals.
USE / ROUTE OF ADMINISTRATION Oral.
DOSAGE 6.6 mg of pyrantel base / kg bw / day, equal to 5 g of oral paste per 100 kg of live weight, in a single administration, is effective in nematode infestations; at double dosage it is effective in tapeworm infestations. Infestations sustained by large and small strongyls Administer 5 g of oral paste per 100 kg of equine weight with a single treatment. Infestations sustained by tapeworms (TENIE) Administer with a single treatment 10 g of pasta per 100 kg of equine weight. Using the 35 g and 50 g syringe Prepare the syringe for dispensing the correct dose based on the weight of the horse. The precise delivery of the dose to be administered is obtained by positioning the anterior margin of the plunger ring in correspondence with the weight of the equine indicated on the graduated scale referring to infestations by strongyles or cestodes. Using the 300 g tube Insert the tube onto the special dispensing gun. Set up the gun by positioning the dosage regulator in the minimum (6.6 g), medium (10 g) or maximum (13.5 g) position dosed according to the weight of the horse and the dose to be administered, according to the tables below .
STORAGE Store in closed container. Shelf life after first opening the primary packaging: 30 days.
WARNINGS Parasite resistance to any class of anthelmintics may develop after frequent and repeated use of an anthelmintic of that class. In order to achieve effective parasite control, treatment should be carried out based on the results of the parasitological examination of the stool. In debilitated or heavily infested animals, the product should only be used after a benefit / risk assessment. Digestive bleeding (diarrhea, bloody stools) can result from treatment with anthelmintics in case of heavy infestations. The active ingredient is not known to cause particular adverse reactions in young animals. Special precautions to be taken by the person administering the product to animals: in case of ingestion or spilling on the skin, seek medical advice immediately and show the package leaflet or the label. Wear gloves to administer the product. In case of accidental contact, wash your hands thoroughly. People with known hypersensitivity to any of the excipients should avoid contact with the veterinary medicinal product. Overdose: No symptoms of any kind occurred following administration up to 6 times the therapeutic dose for 3 consecutive days. At dosages higher than those recommended, a significant increase in ALT values was recorded. Incompatibility: in the absence of compatibility studies, do not mix with other veterinary medicinal products.
WAITING TIME Meat, offal: zero days.
TARGET SPECIES Equines.
INTERACTIONS In particularly debilitated subjects the concomitant administration of the product associated with other cholinergic drugs could accentuate the nicotine-like effects of Pyrantel, enhancing its toxicity. Do not use simultaneously with piperazine, as the anthelmintic effects of pyrantel can be counteracted by piperazine.
SIDE EFFECTS The most frequently observed side effects are correlated with the gastrointestinal system, in particular: anorexia, vomiting, diarrhea. In severely debilitated subjects the nicotinic effects of pyrantel are more pronounced.
PREGNANCY AND BREASTFEEDING It is well tolerated during all stages of pregnancy and lactation as well as weaning.
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