ACTIVE PRINCIPLES Infancy 2.25 rectal solution: each single-dose container contains glycerol 2.25 g. Adults 6.75 g rectal solution: each single-dose container contains 6.75 g glycerol.
INDICATIONS Short-term treatment of occasional constipation.
CONTRAINDICATIONS / SECONDARY EFFECT Hypersensitivity 'to the active substance or to any of the excipients. Acute abdominal pain or of unknown origin, nausea or vomiting, intestinal obstruction or stricture, rectal bleeding of unknown origin, acute haemorrhoidal crisis with pain and bleeding, severe dehydration.
DOSAGE The correct dose is the minimum sufficient to produce an easy evacuation. It is advisable to initially use the minimum doses provided. Adults and adolescents (12-18 years): 1 single-dose container of 6.75 g adults as needed, for a maximum of 1 or 2 doses per day Children aged 2-6 years: 1 single-dose container of 2 infants , 75 g as needed, for a maximum of 1 or 2 administrations per day. Instructions for use: it may be useful to lubricate the cannula with a drop of the solution itself, before introducing it into the rectum and pressing the bellows. Remove the cannula while pressing the bellows. Each container should be used for one administration only; any remaining medicine must be discarded. In children under the age of twelve, the medicine can be used only after consulting a doctor. Laxatives should be used as infrequently as possible and for no more than seven days. A diet rich in liquids favors the effect of the medicine.
STORAGE Store in the original package to protect the medicine from humidity and away from direct heat sources.
WARNINGS Laxatives should be used as infrequently as possible and for no more than seven days. Use for longer periods of time requires a doctor's prescription after adequate evaluation of the individual case. The treatment of chronic or recurrent constipation always requires the intervention of the doctor for the diagnosis, the prescription of drugs and the surveillance during the course of therapy. It is also advisable that elderly people or those in poor health conditions consult their doctor before using the medicine. The abuse of laxatives can cause persistent diarrhea with consequent loss of water, mineral salts (especially potassium) and other essential nutritional factors. In severe cases of abuse, the onset of dehydration or hypokalemia is possible, which can lead to cardiac or neuromuscular dysfunctions, especially in the case of concomitant treatment of glycosidicardiacs, diuretics or corticosteroids. The abuse of laxatives, especially contact laxatives (stimulant laxatives), can cause addiction (and, therefore, possible need to gradually increase the dosage), chronic constipation and loss of normal intestinal functions (intestinal atony). In episodes of constipation, it is advisable first of all to correct eating habits by integrating the daily diet with an adequate intake of fiber and water. In episodes of dystopia, it is first of all recommended to correct eating habits by integrating the daily diet with an adequate intake of fiber and water. When using laxatives it is advisable to drink at least 6-8 glasses of water or other liquids per day, in order to favor the softening of the stool.
INTERACTIONS No specific interaction studies have been performed.
SIDE EFFECTS Gastrointestinal disorders: isolated cramping pains or abdominal colic and diarrhea, with loss of fluids and electrolytes, more frequent in cases of severe constipation, as well as rectal irritation.
PREGNANCY AND BREASTFEEDING There have been no adequate and well-controlled studies on the use of the medicine in pregnancy or lactation. Although there are no obvious contraindications to the use of the medicine during pregnancy and lactation, it is recommended to take the medicine only in case of need and under medical supervision.
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