Frontline Tri-Act Spot-On Solution Dogs 40-60 kg 6 Single-dose Pipettes

Active principles:

FIPRONIL / PERMETRINA

Therapeutic indications:

For the treatment and prevention of flea and / or tick infestations where repellent (anti-feeding) activity against sand flies, horse flies and / or mosquitoes is necessary. For the treatment and prevention of Ctenocephalides felis flea infestations and the prevention of Ctenocephalides canis flea infestations. The product eliminates C. felis fleas present on the animal within 24 hours. One treatment prevents subsequent flea infestations for 4 weeks. The product can be used as part of a strategic treatment for flea allergy dermatitis where it has been previously diagnosed by a veterinarian. The product has a repellent efficacy against ticks (Dermacentorreticulatus) from 7 days and up to 4 weeks after treatment. However, single ticks can attach to the dog and detach within the first 24 hours of infestation. The product has an immediate acaricidal efficacy against Rhipicephalus sanguineus and Ixodes ricinus but it is possible that not all ticks are eliminated within 48 hours of treatment if these are already present at the time of application of the product. The product has an acaricidal efficacy against ticks (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus) persistent for 4 weeks. The product has a repellent (anti-feeding) efficacy for 3 weeks against sand flies (Phlebotomus perniciosus) and for 4 weeks against mosquitoes (Culex pipiens). The product has a persistent insecticidal efficacy for 3 weeks against sand flies (Phlebotomus perniciosus). The product repels and kills horseflies (Stomoxys calcitrans) for five weeks.

Contraindications / Undesirable Effects:

Do not use in sick or convalescent animals. Do not use in cats or rabbits, as potentially fatal adverse reactions may occur. Do not use in case of known hypersensitivity to the active substances or to any of the excipients.

Dosage:

For topical skin application. Animals should always be treated with the correct size pipette corresponding to their body weight. For dogs weighing more than 60 kg, use the correct combination of two pipette sizes, which matches the dog's body weight as closely as possible. Treatment program: the use of the product must be based for the treatment of a confirmed infestation or on a risk of infestation by fleas and / or ticks, where repellent (anti-feeding) activity against sand flies is also necessary. and / or mosquitoes and / or horse flies. Repeat treatment may be indicated depending on the exposure to ectoparasites. In these cases, the interval between two consecutive treatments should be at least 4 weeks.

Storage:

Store in the original blister. Do not store above 25 degrees C.

Warnings:

It is possible for single ticks to attack or single sand flies or mosquitoes to bite the dog. For this reason, if particularly unfavorable conditions occur, it is not possible to completely exclude the transmission of pathogens through these arthropods. The product retains its efficacy against fleas when treated animals are subjected to occasional immersion in water (e.g. swimming, bathing). However, it is advisable not to wash or allow dogs to swim for 48 hours after treatment. Avoid subjecting treated dogs to frequent baths or washing, as these can negatively affect the maintenance of the efficacy of the product. To reduce re-infestation due to the appearance of new fleas, it is recommended to treat all cohabiting dogs. Other animals living in the same house must also be treated with a suitable product. To further contribute to reducing environmental infestation, we also recommend the use of an environmental treatment aimed at adult fleas and their relative larval stages. In the absence of specific studies, the use of the product is not recommended in dogs less than 8 weeks of age, or in dogs weighing less than 2 kg. Be careful to avoid contact of the product with the dog's eyes. It is important to make sure that the product is applied in an area where the animal cannot lick itself and to make sure that other animals do not lick the treated area after application. In cats the product can 'cause potentially fatal convulsions, due to the presence of permethrin. In case of accidental skin exposure, wash the cat with shampoo or soap and seek immediate veterinary care. To prevent cats from being accidentally exposed to the product, separate treated dogs from cats until the application site is dry. It is important to ensure that cats do not lick the application site of a dog that has been treated with this product. Should such exposure occur, seek immediate veterinary care. The product can have negative effects on aquatic organisms. Do not allow treated dogs to enter water courses for 2 days following treatment. Special precautions to be taken by the person administering the product to animals: this product can cause irritation to the skin and eyes. Therefore, avoid that the product comes into contact with the skin and eyes. Do not open the pipette towards or near your face. In case of ocular exposure or if the eyes become irritated during administration, rinse immediately with plenty of water. If eye irritation persists, consult a doctor. In case of skin exposure or if the skin becomes irritated during administration of the product, immediately wash the skin thoroughly with soap and water. If skin irritation persists or recurs, seek medical attention. People with known hypersensitivity to fipronil and / or permethrin should avoid contact with the product. The product is harmful if swallowed. Avoid hand-mouth contact. Do not smoke, drink or eat during application. Wash hands after use. If swallowed, if you feel unwell, rinse your mouth and consult a doctor. Since in case of significant exposure, the excipient N-methylpyrrolidone can induce fetotoxicity and teratogenicity, pregnant women should wear gloves to avoid contact with the product. Treated animals should not be touched until the application site is dry and children should not be allowed to play with treated animals until the application site is dry. It is therefore recommended not to treat the animals during the day but to treat them in the early evening hours and not to allow the newly treated animals to sleep with their owners, especially with children. Store pipettes in the original blister and, after use, empty pipettes must be disposed of correctly immediately to prevent further access. Overdose: Safety has been demonstrated at doses up to 5 times the maximum exposure dose in healthy adult dogs and puppies. Transient side effects such as mild neurological disturbances, emesis and diarrhea may occur but resolve without treatment within 1-2 days.

Side effects:

Among the very rare adverse reactions, transient skin reactions at the application site (skin discoloration, local alopecia, pruritus, redness) and generalized pruritus or alopecia have been reported after use. Excessive salivation, reversible neurological disorders (increased sensitivity to stimuli, hyperactivity, muscle tremor, depression, other nervous disorders) or vomiting have also been observed after use. If the dog were to lick the application site, transient hypersalivation and emesis may be observed.

Target species:

Dogs