Frontline Tri-act Spot-on Solution Dogs 40-60 Kg 3 Single-dose Pipettes

WARNINGS

Special warnings for each target species

It is possible for single ticks to attach themselves or for single sand flies or mosquitoes to bite the dog. For this reason, in the event of particularly unfavorable conditions, it is not possible to completely exclude the transmission of pathogens through these arthropods. The product retains its efficacy against fleas when treated animals are subjected to occasional immersion in water (e.g. swimming, bathing). However, it is advisable not to wash or allow dogs to swim for 48 hours after treatment. Avoid subjecting treated dogs to frequent baths or washing, as these can negatively affect the maintenance of the effectiveness of the product.

To reduce re-infestation due to the appearance of new fleas, it is recommended to treat all cohabiting dogs. Other animals living in the same house must also be treated with a suitable product. To further contribute to reducing environmental infestation, it is advisable, in addition, to use an environmental treatment aimed at adult fleas and their relative larval stages.

Special precautions for use in animals

In the absence of specific studies, the use of the product is not recommended in dogs less than 8 weeks of age, or in dogs weighing less than 2 kg.

Be careful to avoid contact of the product with the dog's eyes.

It is important to ensure that the product is applied in an area where the animal cannot lick itself and to ensure that other animals do not lick the treated area after application.

In cats the product can cause life-threatening convulsions due to the presence of permethrin. In case of accidental skin exposure, wash the cat with shampoo or soap and seek immediate veterinary care.

To prevent cats from being accidentally exposed to the product, separate treated dogs from cats until the application site is dry. It is important to ensure that cats do not lick the application site of a dog that has been treated with this product. Should such exposure occur, seek immediate veterinary care.

Special precautions for whoever administers the product

For veterinary use only.

May cause skin and eye irritation. Therefore, avoid that the product comes into contact with the skin and eyes. Do not open the pipette towards or near your face. In case of ocular exposure or if the eyes become irritated during administration, rinse immediately with plenty of water. If eye irritation persists, consult a doctor. In case of skin exposure or if the skin becomes irritated during administration of the product, immediately wash the skin thoroughly with soap and water. If skin irritation persists or recurs, seek medical attention. People with known hypersensitivity to fipronil and / or permethrin should avoid contact with the product.

The product is harmful if swallowed. Avoid hand-to-mouth contact. Do not smoke, drink or eat during application. Wash hands after use. If swallowed, if you feel unwell, rinse your mouth and consult a doctor.

Since in case of significant exposure, the excipient N-methylpyrrolidone can induce foetotoxicity and teratogenicity, pregnant women should wear gloves to avoid contact with the product.

Treated animals should not be touched until the application site is dry and children should not be allowed to play with treated animals until the application site is dry. It is therefore recommended not to treat the animals during the day but to treat them in the early evening hours and not to allow the newly treated animals to sleep with their owners, especially with children. Store pipettes in the original blister and, after use, empty pipettes must be disposed of correctly immediately to prevent further access.

PARAPHARMACEUTICAL CATEGORY

Veterinary medicine.

STORAGE

Keep out of the sight and reach of children.

Store in the original blister.

Do not store above 25 ° C.

CONTRAINDICATIONS / SECONDARY EFFECTS

Do not use in sick or convalescent animals.

Do not use in cats or rabbits, as potentially life-threatening adverse reactions may occur.

Do not use in case of known hypersensitivity to the active substances or to any of the excipients.

NAME

Frontline Tri-Act spot-on solution for dogs 40-60 kg

EXCIPIENTS

Butylhydroxytoluene (E321) (mg) 6,750

SIDE EFFECTS

Among the very rare adverse reactions, transient skin reactions at the application site (skin discoloration, local alopecia, pruritus, redness) and generalized pruritus or alopecia have been reported after use.

Excessive salivation, reversible neurological disorders (increased sensitivity to stimuli, hyperactivity, muscle tremor, depression, other nervous disorders) or vomiting have also been observed after use.

If the dog were to lick the application site, transient hypersalivation and emesis may be observed.

PREGNANCY AND BREASTFEEDING

Laboratory studies conducted with fipronil and permethrin have not shown the existence of teratogenic or embryotoxic effects. Studies with this product have not been performed in pregnant or lactating animals.

N-methylpyrrolidone, an excipient present in the veterinary medicinal product, has been shown to be teratogenic in laboratory animals repeatedly exposed to high doses. Use only in accordance with the benefit / risk assessment by the responsible veterinarian.

INDICATIONS

For the treatment and prevention of flea and / or tick infestations where repellent (anti-feeding) activity against sand flies, horse flies and / or mosquitoes is necessary.

For the treatment and prevention of flea infestations of Ctenocephalides felis and the prevention of flea infestations of Ctenocephalides canis. The product eliminates C. felis fleas present on the animal within 24 hours. One treatment prevents subsequent flea infestations for 4 weeks. The product can be used as part of a strategic treatment for flea allergy dermatitis where it has been previously diagnosed by a veterinarian.

The product has a repellent efficacy against ticks (Dermacentor reticulatus) from 7 days and up to 4 weeks after treatment.

The product has immediate acaricidal efficacy against Rhipicephalus sanguineus and Ixodes ricinus.

The product has an acaricidal efficacy against ticks (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus) persistent for 4 weeks.

The permethrin present in the product provides repellent activity against sand flies (> 80% for 4 weeks).

The product has a repellent efficacy for 4 weeks against mosquitoes (Culex pipiens). The product has a persistent insecticidal efficacy for 3 weeks against sand flies (Phlebotomus perniciosus).

The product repels and kills horseflies (Stomoxys calcitrans) for five weeks.

DOSAGE

For topical skin application (spot-on use).

Frontline Tri-Act

Single dose volume (ml)

Fipronil (mg)

Permethrin (mg)

Very large dogs 40-60 kg

6

405.6

3028.8

ACTIVE PRINCIPLES

fipronil

405.6 mg

permethrin

3028.8 mg

TARGET SPECIES

Dogs.

WAITING TIME

Not relevant.

METHOD OF DISPENSATION

Free sale.

USE / ROUTE OF ADMINISTRATION

Topical.