Benexol Vitamin B Complex 20 gastro-resistant tablets

Benexol Tablets is used in deficient states of vitamins B1, B6 and B12 and their various clinical forms (deficient polyneuritis, neuritis during treatment with isoniazid and other vitamin B6 antagonists). It can be used as adjuvant therapy in non-deficient neuritis and during radiotherapy.

Dosage and method of use
Benexol Tablets should be taken in the following doses and methods:

Adults and children over 12 years of age: 1 tablet per day. Benexol tablets should be swallowed with a sip of liquid, without chewing or dissolving them previously. The product is usually prescribed for periods of one or more weeks. In some cases, the doctor may extend the treatment up to a few months.
Children: due to the high dosage of vitamin B6, the product is contraindicated in children under 12 years
Renal / hepatic insufficiency: due to the high dosage of vitamin B6, the product is contraindicated in patients with renal or hepatic insufficiency

Contraindications

Hypersensitivity to the active substances or to any of the excipients
During pregnancy and breastfeeding
In children under the age of 12
In patients with renal or hepatic insufficiency

Special warnings
Do not exceed the recommended dose and duration of treatment. Due to the high dosage of pyridoxine hydrochloride (vitamin B6), the product should not be taken at higher doses or for longer periods than recommended, as improper use can be associated with severe neurotoxicity. Particular caution should be used when the product is prescribed together with levodopa for the treatment of Parkinson's disease, as pyridoxine in high doses can antagonize its therapeutic effect.

Repeated administration of preparations containing vitamin B1 by the intramuscular route can in rare cases cause anaphylactic reactions in predisposed patients. The clinical picture may in some respects simulate anaphylactic shock. In order to avoid these rare anaphylactic reactions, oral administration should always be preferred, whenever possible. If this is not possible, the intramuscular injection should be done as slowly as possible by qualified and experienced personnel

Pregnancy and breastfeeding
The product is contraindicated during pregnancy and lactation, due to the high dosage of vitamin B6, which greatly exceeds the recommended dietary dosage.

Expiration and retention
Check the expiration date indicated on the package. The expiry date indicated on the package refers to the product in intact packaging, correctly stored. Store at a temperature not exceeding 25 ° C.

Warning: do not use the medicine after the expiry date indicated on the package.

Composition
Benexol Tablets contains:
Active ingredient: thiamine hydrochloride (Vit. B1) 250 mg, pyridoxine hydrochloride (Vit. B6) 250 mg, cyanocobalamin (Vit. B12) 500 µg.
Excipients: colloidal hydrated silica, povidone, magnesium stearate, pregelatinized starch, mannitol, talc, methacrylic acid - ethyl acrylate copolymer (1: 1), carmellose sodium, macrogol 6000, glycerol triacetate.

Benexol in packs of 20 gastro-resistant tablets