Actifed Compound Syrup Symptomatic Treatment Of Cough Bottle 100ml

Actifed compound syrup 100ml

Indications
Symptomatic treatment of cough and congestive affections of the upper respiratory tract, in particular on an allergic basis.

Dosage
Attached to the package is a measuring cup in the shape of a double teaspoon corresponding to the capacities of 2.5 and 5 ml. Adults and children over 12 years: a dose of 10 ml of syrup 2 3 times a day. Do not exceed the recommended dose.

Active principles
100 ml of syrup contain: Active ingredients: Triprolidine hydrochloride 0.025 g; pseudoephedrine hydrochloride 0,600 g; dextromethorphan hydrobromide 0.200 g. For the full list of excipients see section 6.1.

Excipients
Sorbitol (70%) not crystallizable; sucrose; sodium benzoate; methyl parahydroxybenzoate; ponceau 4r (e124); ethanol; blackberry flavor; menthol; vanillin; purified water

Contraindications
Hypersensitivity to the active substances, to other antihistamines or to any of the excipients The drug is contraindicated in children under 12 years of age, during pregnancy, breastfeeding, in patients receiving monoamine oxidase inhibitors (MAOIs) or within two weeks following this treatment, and in the therapy of lower respiratory tract diseases, including bronchial asthma. Due to its anticholinergic effects, do not use in case of glaucoma, prostatic hypertrophy, bladder neck obstruction, pyloric and duodenal stenosis or other tracts of the gastrointestinal and urogenital tract. It is also contraindicated in cardiovascular diseases, arterial hypertension, hyperthyroidism, as well as epilepsy and diabetes. Dextromethorphan, like other central cough suppressants, is contraindicated in patients who present or may develop respiratory failure.

Warnings
If symptoms do not improve within 7 days or if you experience a high fever or other side effects, stop treatment and consult your doctor. At common therapeutic doses, antihistamines exhibit highly variable secondary reactions from subject to subject and from compound to compound. Consult your doctor to determine the dose in the elderly due to their greater sensitivity to antihistamines and to pseudoephedrine. The product contains sucrose, this should be taken into account in case of low calorie diets. The syrup contains methyl parahydroxybenzoate: it can generally cause delayed allergic reactions such as dermatitis; rarely immediate reactions with urticaria and bronchospasm. Although Pseudoephedrine did not produce important effects on blood pressure in normotensive subjects, Actifed Compound should not be taken by patients on antihypertensive, tricyclic antidepressant, sympathomimetic agents, such as decongestants, anorectics, amphetamine-like agents. Actifed Compound should also not be used by patients with severe kidney or liver disease. Keep this medicine out of the reach and sight of children. For those who carry out sporting activities, the use of medicines containing ethyl alcohol can determine positivity to doping tests in relation to the alcohol concentration limits indicated by some sports federations.

Pregnancy
Actifed Compound is contraindicated during pregnancy and lactation.

Side effects
Actifed Compound can cause mainly drowsiness, then asthenia, dizziness, allergic skin rashes, photosensitization, dry mouth, urinary retention, thickening of bronchial secretions, gastrointestinal disorders such as nausea, vomiting and diarrhea, which can be reduced by administering the product after meals, excitation of the CNS, accompanied by insomnia, euphoria and tremors; very rarely blood disorders and, especially in the elderly, headache, extrasystole, tachycardia and hypotension.

Overdose
In case of overdose, marked depressive or stimulating effects on the CNS, drowsiness, lethargy, respiratory depression, hypertension, irritability, convulsions are generally observed. In children the dominant action is the exciting one with marked tremors, insomnia, hyperactivity and convulsions.

Interactions
The effects of antihistamines are made more evident by alcohol, hypnotics, sedatives, tranquilizers, and other substances with anticholinergic action or depressant effect on the central nervous system, which therefore should not be taken during therapy. Antihistamines can reduce the duration of action of oral anticoagulants. The use of antihistamines can mask the early signs of ototoxicity of certain antibiotics. Furazolidone causes a progressive inhibition of monoamine oxidase, so it should not be taken at the same time as the Compound Acttifed. The effect of antihypertensives that interfere with sympathetic activity (e.g. methyldopa, alpha and beta blockers, debrisoquine, guanethidine, betanidine and bretylium) can be partially canceled by the Compound Acttifed, which therefore, also in this case, does not must be taken at the same time.

storage
Store at a temperature not exceeding 25 ° C and protected from light.